Oncology’s energetic pipeline

Short report about Warburg effect in cancer, how and hypothesized why tumors switch from aerobic to anaerobic metabolism. Molecular biology behind it, and industry answer by different drugs. Interesting description of new component, dichloroacetate (DCA), which shifts metabolism from glycolysis to oxidative phosphorylation.

Nat Biotechnol. 2010 Sep;28(9):888-91.

Oncology’s energetic pipeline.

Garber K.

PMID: 20829819

This entry was posted on October 3, 2010 at 8:21 pm and is filed under Cancer, Microenvironment. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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